ANA Blood Test Autoimmune
Mar 8, 2026
ANA Blood Test Autoimmune
An ANA (antinuclear antibody) blood test detects antibodies that attack your own cells, screening for autoimmune conditions like systemic lupus erythematosus (SLE), Sjögren's syndrome, scleroderma, and mixed connective tissue disease—conditions where the immune system mistakenly attacks the body's own tissues. A positive ANA doesn't diagnose a specific disease but indicates the need for further investigation.
At Blood Test London, ANA testing costs from £265 with results in 2-3 days. A doctor always reviews every result, explaining what positive or negative results mean.
What Does ANA Test For?
Conditions Associated with Positive ANA
Condition | ANA Positive Rate | Key Symptoms |
|---|---|---|
Systemic lupus (SLE) | 95-99% | Joint pain, fatigue, rash, kidney issues |
Sjögren's syndrome | 70-80% | Dry eyes, dry mouth, fatigue |
Scleroderma | 60-90% | Skin hardening, Raynaud's |
Mixed connective tissue disease | 95% | Features of multiple conditions |
Rheumatoid arthritis | 30-40% | Joint inflammation |
Autoimmune hepatitis | 50-70% | Liver inflammation |
Hashimoto's thyroiditis | 40-50% | Thyroid underactivity |
Understanding ANA Results
Titre (Concentration)
Titre | Interpretation |
|---|---|
Negative | No ANA detected |
1:40 | Low positive (often not significant) |
1:80 | Borderline (may be significant) |
1:160 | Moderate positive |
1:320+ | Strong positive (more likely significant) |
Pattern (If Positive)
Pattern | Associated Conditions |
|---|---|
Homogeneous | SLE, drug-induced lupus |
Speckled | Sjögren's, mixed CTD, SLE |
Nucleolar | Scleroderma |
Centromere | Limited scleroderma (CREST) |
Important: ANA Limitations
Positive ANA doesn't mean autoimmune disease
15-20% of healthy people have low-positive ANA
Titre and pattern matter
Clinical symptoms are essential for diagnosis
Further specific antibodies may be needed
When to Test
Joint pain and swelling
Unexplained fatigue
Skin rashes
Dry eyes and mouth
Raynaud's phenomenon
Hair loss
Kidney problems
Family history of autoimmune disease
Our Autoimmune Testing Options
Basic ANA Screen - £265
ANA with titre and pattern
Doctor review
Autoimmune Panel - £395
ANA
Anti-dsDNA (specific for lupus)
ENA panel
Rheumatoid factor
CRP
Comprehensive Autoimmune - £545
Full autoimmune panel
Thyroid antibodies
Complement levels
Full blood count
Extended consultation
Book Your ANA Test
Price: From £265
Results: 2-3 days
Doctor review: A doctor always reviews every result
Book via WhatsApp | Phone: 020 3951 3429
Blood Test London by The Wellness. ANA autoimmune testing from £265. A doctor always reviews every result.