Cortisol Stress Hormone Test
Feb 3, 2026

Cortisol Stress Hormone Test
A cortisol blood test measures your body's primary stress hormone, produced by the adrenal glands—with abnormal levels (either high or low) causing symptoms including chronic fatigue, weight gain (especially belly fat), anxiety, depression, sleep disturbance, and weakened immunity. Because cortisol follows a natural daily rhythm (highest in the morning, lowest at night), testing timing matters.
At Blood Test London, cortisol testing costs from £245 with results in 2-3 days.
Understanding Cortisol: Your Stress Hormone
Cortisol is essential for life—it helps you:
Wake up in the morning
Respond to stress
Regulate blood sugar
Control inflammation
Maintain blood pressure
Support immune function
The Problem: Chronic Stress
Modern life often keeps cortisol elevated chronically, leading to:
Weight gain (especially abdominal)
Muscle breakdown
Weakened immunity
Poor sleep
Anxiety and depression
Brain fog
Accelerated aging
Normal Cortisol Levels
Morning Cortisol (8-9am) - Best Time to Test
Level (nmol/L) | Interpretation |
|---|---|
170-500 | Normal morning range |
Below 170 | Low—investigate adrenal insufficiency |
Above 500 | High—investigate Cushing's or chronic stress |
Cortisol Daily Rhythm
Time | Expected Level |
|---|---|
8am | Highest (peak) |
12pm | Declining |
4pm | Lower |
Midnight | Lowest (trough) |
Testing should be done at 8-9am for standard assessment.
Signs of Cortisol Imbalance
High Cortisol Symptoms
Weight gain, especially around the middle
Round "moon" face
Thin skin that bruises easily
Muscle weakness
High blood pressure
High blood sugar
Mood changes (anxiety, irritability)
Difficulty sleeping
Reduced libido
Irregular periods
Low Cortisol Symptoms
Extreme fatigue (not relieved by sleep)
Muscle weakness
Weight loss and poor appetite
Low blood pressure
Dizziness when standing
Salt cravings
Darkening of skin
Depression
Brain fog
Conditions Affecting Cortisol
Causes of High Cortisol
Chronic stress (most common)
Cushing's syndrome (overproduction)
Pituitary tumours (ACTH-producing)
Adrenal tumours (cortisol-producing)
Steroid medications (prednisone, etc.)
Depression, alcoholism, obesity (can elevate cortisol)
Causes of Low Cortisol
Addison's disease (adrenal insufficiency)
Pituitary problems (secondary insufficiency)
Stopping steroid medication (suppressed adrenals)
Adrenal fatigue (controversial but some believe chronic stress depletes adrenals)
How to Optimise Cortisol Naturally
For High Cortisol
Strategy | How It Helps |
|---|---|
Sleep 7-9 hours | Allows cortisol to normalise overnight |
Meditation/mindfulness | Proven to lower cortisol |
Exercise (moderate) | Reduces stress, but avoid overtraining |
Limit caffeine | Especially after 12pm |
Reduce alcohol | Disrupts cortisol rhythm |
Adaptogens | Ashwagandha has evidence for lowering cortisol |
Social connection | Reduces stress hormones |
Nature exposure | 20 minutes in nature lowers cortisol |
For Low Cortisol
Address underlying cause (medical evaluation essential)
Gentle exercise (not intense)
Adequate salt intake
Regular meal times
Stress management
Possible medication (hydrocortisone replacement if Addison's)
Our Cortisol Testing Options
Morning Cortisol - £265
Single morning cortisol
Doctor review
Cortisol + DHEA - £295
Cortisol and DHEA-S (adrenal function pair)
Cortisol:DHEA ratio
Full Adrenal Profile - £345
Morning cortisol
DHEA-S
ACTH (pituitary driver)
Doctor review and consultation
Stress & Energy Panel - £395
Adrenal hormones
Thyroid function
Key vitamins (D, B12, iron)
Book Your Cortisol Test
Price: From £245
Results: 2-3 days
Doctor review: A doctor always reviews every result
Requirements: Test at 8-9am, before eating or exercising
Phone: 020 3951 3429
FAQ
What time should I test cortisol?
8-9am for morning cortisol (the standard test). Avoid eating, exercising, or caffeine before the test.
Is "adrenal fatigue" real?
It's controversial. While not a recognized medical diagnosis, chronic stress does affect adrenal function. We test the measurable hormones.
Can stress really affect my health this much?
Yes—chronic cortisol elevation is linked to obesity, diabetes, heart disease, immune dysfunction, and mental health problems.
How long does it take to normalise cortisol?
With lifestyle changes, improvements can be seen in weeks to months. It depends on severity and underlying causes.
Should I test cortisol if I'm stressed?
If stress is causing symptoms, testing helps determine if cortisol is actually elevated and guides treatment.
Blood Test London by The Wellness. Cortisol stress testing from £245, results in 2-3 days.