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Homocysteine Blood Test

Mar 9, 2026

Homocysteine Blood Test

A homocysteine blood test measures this amino acid that, when elevated, is associated with increased risk of cardiovascular disease, stroke, blood clots, dementia, and pregnancy complications—with the good news being that high homocysteine is often easily reducible through B vitamin supplementation (B12, folate, B6). Unlike cholesterol, homocysteine isn't routinely tested, meaning many people have elevated levels without knowing.

At Blood Test London, homocysteine testing costs from £265 with results in 2-3 days. A doctor always reviews every result.

Check Your Homocysteine Level

Why Homocysteine Matters

Health Risks of Elevated Homocysteine

Risk

Association

Heart disease

Independent risk factor

Stroke

Increased risk with high levels

Blood clots (DVT, PE)

Promotes clotting

Dementia/Alzheimer's

Linked to cognitive decline

Pregnancy complications

Neural tube defects, miscarriage

Osteoporosis

Affects bone structure

Homocysteine Reference Ranges

Level (μmol/L)

Interpretation

Below 7

Optimal

7-10

Normal

10-15

Mildly elevated

15-30

Moderately elevated

Above 30

Severely elevated

For longevity optimisation, many experts recommend below 8 μmol/L.

Causes of Elevated Homocysteine

Cause

Mechanism

B12 deficiency

Required for homocysteine metabolism

Folate deficiency

Required for homocysteine metabolism

B6 deficiency

Involved in metabolism

MTHFR gene variants

Impaired folate processing

Kidney disease

Reduced clearance

Hypothyroidism

Slowed metabolism

Certain medications

Methotrexate, metformin, PPIs

How to Lower Homocysteine

B Vitamins (Most Effective)

Vitamin

Recommended Form

Folate

Methylfolate (not folic acid if MTHFR)

B12

Methylcobalamin

B6

Pyridoxal-5-phosphate

Diet

  • Leafy green vegetables (folate)

  • Meat, fish, eggs (B12)

  • Fortified foods

  • Reduce alcohol

Who Should Test?

  • Family history of early heart disease

  • Previous stroke or heart attack

  • Blood clots (DVT, PE)

  • Cognitive decline concerns

  • Recurrent miscarriage

  • Vegan/vegetarian (B12 risk)

  • MTHFR gene variants known

  • Cardiovascular risk optimisation

Book Your Homocysteine Test

Price: From £265
Results: 2-3 days
Doctor review: A doctor always reviews every result

Book via WhatsApp | Phone: 020 3951 3429

Blood Test London by The Wellness. Homocysteine testing from £265. A doctor always reviews every result.